孟祥宗
发布人:网站管理员  发布时间:2019-07-01   浏览次数:22293


1.  个人简介:


孟祥宗:博士,教授,生物化学与分子生物学专业,博士生导师。主要以拟南芥和番茄为材料研究植物免疫信号传导通路和抗病分子机制,揭示了植物中多个重要蛋白激酶介导植物免疫信号传导及调控植物抗病性的机理机制。已在Plant Cell等主流学术期刊发表论文40余篇。2021年获“卫志明青年创新奖”。目前担任上海师范大学生命科学学院副院长、上海市植物分子科学重点实验室主任。


教育经历:

2006-2010:博士,中国科学院上海植物生理与生态研究所

2003-2006:硕士,上海大学

1999-2003:学士,聊城大学


工作经历:

2019-至今:上海师范大学,教授

2016-2019:上海大学,教授

2013-2016:美国德州农工大学,博士后

2010-2013:美国密苏里大学,博士后


2.  教学工作


[1]本科生课程:《分子生物学》、《生命科学研究动态》

[2]研究生课程:《生命科学研究前沿进展》、《分子生物学实验方法与技术》


3.  主要研究方向:


[1]植物免疫信号传导

[2]植物抗病分子机制

[3]植物抗病基因工程


4.  代表性科研项目:


[1]国家“海外高层次人才引进计划”青年项目,2016-2018

[2]国家自然科学基金面上项目(31671515),2017-2020

[3]国家自然科学基金面上项目(31970282),2020-2023

[4]国家自然科学基金面上项目(32170286),2022-2025


5.  学术期刊兼职


[1]2023-至今:《Molecular Plant-Microbe InteractionsAssociate Editor

[2]2022-至今:《Frontiers in Plant ScienceAssociate Editor

[3]2022-至今:《GenesSection Editor


6.  代表性论文


通讯作者论文# corresponding author


[1]He Y., Meng X#. Dual function of the CHS3-CSA1 immune receptor pair. Trends in Plant Science 2023.


[2]He Y*, He X*, Wang X, Hao M, Gao J, Wang Y, Yang ZN, Meng X#. An EPFL peptide signaling pathway promotes stamen elongation via enhancing filament cell proliferation to ensure successful self-pollination in Arabidopsis thaliana.New Phytologist 2023,.


[3]Zhou J., Mu Q., Wang X., Zhang J., Yu H., Huang T., He Y., Dai S., Meng X#. Multilayered synergistic regulation of phytoalexin biosynthesis by ethylene, jasmonate, and MAPK signaling pathways in Arabidopsis. Plant Cell 2022, 34(8): 3066-3087.


[4]Wang X., Meng H., Tang Y., Zhang Y., He Y., Zhou J., Meng X#. Phosphorylation of an ethylene response factor by MPK3/MPK6 mediates negative feedback regulation of pathogen-induced ethylene biosynthesis in Arabidopsis. 空空Journal of Genetics and Genomics 2022, 49(8): 810-822.


[5]Wang X., Zhang N., Zhang L., He Y., Cai C., Zhou J., Li J., Meng X#. Perception of the pathogen-induced peptide RGF7 by the receptor-like kinases RGI4 and RGI5 triggers innate immunity in Arabidopsis thaliana. New Phytologist 2021, 230(3): 1110-1125.


[6]Zhou J., Wang X., He Y., Sang T., Wang P., Dai S. Zhang S., Meng X#. Differential Phosphorylation of the Transcription Factor WRKY33 by the Protein Kinases CPK5/CPK6 and MPK3/MPK6 Cooperatively Regulates Camalexin Biosynthesis in Arabidopsis. Plant Cell 2020, 32(8): 2621-2638.


[7]He Y., Meng X#. MAPK signaling: emerging roles in lateral root formation. Trends in Plant Science 2020, 25(2): 126-129.


[8]He Y., Xu J., Wang X., He X., Wang Y., Zhou J., Zhang S., Meng X#. The Arabidopsis Pleiotropic Drug Resistance Transporters PEN3 and PDR12 Mediate Camalexin Secretion for Resistance to Botrytis cinerea. Plant Cell 2019, 31(9): 2206-2222.


[9]He Y., Zhou J., Meng X#. Phosphoregulation of Ca2+ Influx in Plant Immunity. Trends in Plant Science 2019, 24(12): 1067-1069.


[10]He Y., Zhou J., Shan L.#, Meng X#. Plant cell surface receptor-mediated signaling: a common theme amid diversity. Journal of Cell Science 2018, 131(2): jcs209353.


第一作者论文* co-first author


[1]Meng X., Zhou J., Tang J., Li B., de Oliveira M.V., Chai J., He P., and Shan L. Ligand-Induced Receptor-like Kinase Complex Regulates Floral Organ Abscission in Arabidopsis. Cell Reports 2016, 14(6): 1330-1338.


[2]Li B. *, Meng X.*, Shan L., and He P. Transcriptional Regulation of Pattern-Triggered Immunity in Plants.

Cell Host & Microbe 2016, 19(5): 641-650.


[3]Meng X., Chen X., Mang H., Liu C., Yu X., Gao X., Torii K.U., He P., and Shan L. Differential function of Arabidopsis SERK family receptor-like kinases in stomatal patterning. Current Biology 2015, 25(18): 2361-2372.


[4]Meng X., Shan L., and He P. Stack Heterotrimeric G Proteins and MAPK Cascades on a RACK. Molecular Plant 2015, 8(12): 1691-1693.


[5]Meng X.*, Xu J.*, He Y., Yang K.-Y., Mordorski B., Liu Y., and Zhang S. Phosphorylation of an ERF Transcription Factor by Arabidopsis MPK3/MPK6 Regulates Plant Defense Gene Induction and Fungal Resistance. Plant Cell 2013, 25(3): 1126-1142.


[6]Meng X., and Zhang S. MAPK cascades in plant disease resistance signaling. Annual Review of Phytopathology 2013, 51: 245-266.


[7]Meng X., Wang H., He Y., Liu Y., Walker J.C., Torii K.U., and Zhang S. A MAPK cascade downstream of ERECTA receptor-like protein kinase regulates Arabidopsis inflorescence architecture by promoting localized cell proliferation.

Plant Cell 2012, 24(12): 4948-4960.


[8]Li G.*, Meng X.*, Wang R.*, Mao G., Han L., Liu Y., and Zhang S. Dual-level regulation of ACC synthase activity by MPK3/MPK6 cascade and its downstream WRKY transcription factor during ethylene induction in Arabidopsis.

PLoS Genetics 2012, 8(6): e1002767.


[9]Meng X., Xu Z., and Song R. Molecular cloning and characterization of a vacuolar H+-pyrophosphatase from Dunaliella viridis. Molecular Biology Reports 2011, 38(5): 3375-3382.


[10]Meng X., Huang B., Zhou L., He Y., Chen Q., Yuan Y., Xu Z., and Song R. Construction of a Coix BAC library and isolation of the 22 kDa α-coixin gene cluster. Genome 2010, 53(9): 667-674.


[11]Sun X.*, Meng X.*, Xu Z., and Song R. Expression of the 26S proteasome subunit RPN10 is upregulated by salt stress in Dunaliella viridis. Journal of Plant Physiology 2010, 167(12): 1003-1008.


[12]He Y.*,Meng X.*, Fan Q., Sun X., Xu Z., and Song R. Cloning and characterization of two novel chloroplastic glycerol-3-phosphate dehydrogenases from Dunaliella viridis. Plant Molecular Biology 2009, 71(1-2): 193-205.


共同作者论文


[1]Xu G., Meng X., and Dou D. Differential Ubiquitination of BIK1 Fine-Tunes Plant Immunity.

Trends in Plant Science 2021, 26(1): 2-4.


[2]Zhou J., Wang P., Claus L.A.N., Savatin D.V., Xu G., Wu S., Meng X., Russinova E., He P., and Shan L. Proteolytic processing of SERK3/BAK1 regulates plant immunity, development and cell death. Plant Physiology 2019, 180(1): 543-558.


[3]Zhou J., Liu D., Wang P., Ma X., Lin W., Chen S., Mishev K., Lu D., Kumar R., Vanhoutte I., Meng X., He P., Russinova E., and Shan L. Regulation of Arabidopsis brassinosteroid receptor BRI1 endocytosis and degradation by plant U-box PUB12/PUB13-mediated ubiquitination. Proc. Natl. Acad. Sci. U. S. A. 2018, 115(8): E1906-E1915.


[4]Fan J., Bai P., Ning Y., Wang J., Shi X., Xiong Y., Zhang K., He F., Zhang C., Wang R., Meng X., Zhou J., Wang M., Shirsekar G., Park C.H., Bellizzi M., Liu W., Jeon J.S., Xia Y., Shan L., and Wang G.L. The Monocot-Specific Receptor-like Kinase SDS2 Controls Cell Death and Immunity in Rice. Cell Host & Microbe 2018, 23(4): 498-510.


[5]Mang H., Feng B., Hu Z., Boisson-Dernier A., Franck C.M., Meng X., Huang Y., Zhou J., Xu G., Wang T., Shan L., and He P. Differential Regulation of Two-Tiered Plant Immunity and Sexual Reproduction by ANXUR Receptor-Like Kinases. 空空Plant Cell 2017, 29(12): 3140-3156.


[6]Xu J., Meng J., Meng X., Zhao Y., Liu J., Sun T., Liu Y., Wang Q., and Zhang S. Pathogen-Responsive MPK3 and MPK6 Reprogram the Biosynthesis of Indole Glucosinolates and Their Derivatives in Arabidopsis Immunity. Plant Cell 2016, 28(5): 1144-1162.


[7]de Oliveira M.V., Xu G., Li B., de Souza Vespoli L., Meng X., Chen X., Yu X., de Souza S.A., Intorne A.C., de A Manhães A.M., Musinsky A.L., Koiwa H., de Souza Filho G.A., Shan L., and He P. Specific control of Arabidopsis BAK1/SERK4-regulated cell death by protein glycosylation. Nature Plants 2016, 2: 15218.


[8]Guan R., Su J., Meng X., Li S., Liu Y., Xu J., and Zhang S. Multilayered Regulation of Ethylene Induction Plays a Positive Role in Arabidopsis Resistance against Pseudomonas syringae. Plant Physiology 2015, 169(1): 299-312.


[9]Li F., Cheng C., Cui F., de Oliveira M.V., Yu X., Meng X., Intorne A.C., Babilonia K., Li M., Li B., Chen S., Ma X., Xiao S., Zheng Y., Fei Z., Metz R.P., Johnson C.D., Koiwa H., Sun W., Li Z., de Souza Filho G.A., Shan L., and He P. Modulation of RNA polymerase II phosphorylation downstream of pathogen perception orchestrates plant immunity.

Cell Host & Microbe 2014, 16(6): 748-758.


[10]Guan Y., Meng X., Khanna R., LaMontagne E., Liu Y., and Zhang S. Phosphorylation of a WRKY transcription factor by MAPKs is required for pollen development and function in Arabidopsis. PLoS Genetics 2014, 10(5): e1004384.


[11]Mao, G., Meng, X., Liu, Y., Zheng, Z., Chen, Z., and Zhang, S. Phosphorylation of a WRKY transcription factor by two pathogen-responsive MAPKs drives phytoalexin biosynthesis in Arabidopsis. Plant Cell 2011, 23(4): 1639-1653.


7.  欢迎加入

[1]本实验室招聘讲师或副教授(根据学习工作经历和科研成果确定),在拟南芥和番茄中开展植物抗病分子机制研究,有意应聘者请发个人简历至xzmeng@shnu.edu.cn

[2]欢迎对本实验室感兴趣的博士、硕士研究生及本科生加入我们!本实验室是一个年轻且富有朝气的科研团队,具有良好的科研氛围和平台及前沿的研究课题,将为有志青年提供优越的发展空间和上升通道。


8.  联系方式:

实验室地址:上海市徐汇区桂林路100号上海师大徐汇校区第一教学楼404

电子邮箱:xzmeng@shnu.edu.cn



更新时间:2023年2月