1. 个人简介：
吴文娟博士，讲师，wwj8255@shnu.edu.cn
教育经历：
2007.8–2011.3，中科院上海植物生理生态研究所，植物学，博士
2005.9–2007.7，中科院上海植物生理生态研究所，植物学，硕士
2001.9–2005.6，南京师范大学，生物科学（理科基地），学士
工作经历：
2017.7-至今, 上海师范大学，生命科学学院，讲师
2015.5-2017.5，美国普渡大学，农学院，实验助理
2014.6-2015.4，中科院上海植物生理生态研究所，助理研究员
2011.3-2014.5，中科院上海植物生理生态研究所，博士后
2. 主要研究方向：
[1] 叶绿体发育和斑叶形成机制
[2] RNA结合蛋白APUM家族的功能研究
3. 代表性科研项目：
[1] 叶绿体分裂在拟南芥斑叶形成中的作用及机制研究 国家自然科学基金青年项目 2022-2024。
[2]拟南芥RNA结合蛋白APUM家族第一亚类的功能与作用机理研究 上海市自然科学基金面上项目 2021-2024。
4. 代表性论文及著作：(#为共同第一作者；*为通讯作者)
[1] Wu, W.#, Guo, W.#, Zhu, H., Li, D., Zhang, Z., Lin, D., Qu, M., Yu, Z., and Huang, J.* (2025). Arabidopsis Leaf variegation is caused by simultaneous defects in chloroplast development and division. Plant Communications.
[2] Zhang, W., Xu, Y., Cui, J., Xue, Y., Zhang, L., Wu, W., Wang, C., and Zhang, H.* (2024). Development of the A&GBE base editor for efficiently generating abundant genetic variation in rice. The Crop Journal 12, 1801-1805.
[3] Suo, Y., Hu, F., Zhu, H., Li, D., Qi, R., Huang, J., and Wu, W.* (2021). BIG3 and BIG5 redundantly mediate vesicle trafficking in Arabidopsis. Biomolecules 11, 732.
[4] Zhu, Y.#, Wu, W.#, Shao, W., Chen, J., Shi, X., Ma, X., Xu, Y.-Z., Huang, W.*, and Huang, J.* (2020). SPLICING FACTOR1 is important in chloroplast development under cold stress. Plant physiology 184, 973-987.
[5] Wu, W.#, Liu, S.#, Ruwe, H., Zhang, D., Melonek, J., Zhu, Y., Hu, X., Gusewski, S., Yin, P., Small, I.D. I.D., Howell, K.*, and Huang, J.* (2016). SOT1, a pentatricopeptide repeat protein with a small MutS‐related domain, is required for correct processing of plastid 23S–4.5 S rRNA precursors in Arabidopsis thaliana. The Plant Journal 85, 607-621.
[6] Wu, W.#, Zhu, Y.#, Ma, Z., Sun, Y., Quan, Q., Li, P., Hu, P., Shi, T., Lo, C., Chu, I.K., and Huang, J.* (2013). Proteomic evidence for genetic epistasis: ClpR4 mutations switch leaf variegation to virescence in Arabidopsis. The Plant Journal 76, 943-956.
[7] Wu,W.#, Elsheery, N.#, Wei, Q.#, Zhang, L., and Huang, J.* (2011). Defective etioplasts observed in variegation mutants may reveal the light‐independent regulation of white/yellow sectors of Arabidopsis leaves. Journal of Integrative Plant Biology 53, 846-857.
[8] Zhang, L.#, Wei, Q.#, Wu, W.#, Cheng, Y., Hu, G., Hu, F., Sun, Y., Zhu, Y., Sakamoto, W., and Huang, J.* (2009). Activation of the heterotrimeric G protein α‐subunit GPA1 suppresses the ftsh‐mediated inhibition of chloroplast development in Arabidopsis. The Plant Journal 58, 1041-1053.
5. 代表性授权专利：
[1] 黄继荣，吴文娟 调节植物叶片转绿过程的蛋白、其编码基因及应用 授权号：ZL200910052370.9 授权日期 2013.10.9
[2] 黄继荣，黄伟华，吴文娟 控制植物叶片转绿的基因及其使用方法和应用 授权号：ZL201210536969.1 授权日期 2016.8.31
更新时间：2025年10月
