邢维满
发布人:网站管理员  发布时间:2019-09-18   浏览次数:11931

  


1. 个人简介:

邢维满 博士,教授,生物化学专业/博士生导师

教育经历:

2000-2007,博士,中国科学院生物物理研究所&北京生命科学研究所

1996-2000学士南开大学生物化学系

工作经历:

    2019-至今,上海师范大学研究员/博士生导师

2014-2019,上海植物逆境生物学研究中心 研究员/博士生导师

2008-2014美国华盛顿大学&霍华德休斯医学研究所 博士后

2. 主要研究方向:

[1]植物病原菌致病机制

[2]植物抗病机制

[3]生物活性小分子的感知机制


3. 代表性科研项目:

 [1] 中组部青千,2015


4. 代表性论文著作:

1. Zhou J, Hu Q, Xiao X, Yao D, Ge S, Ye J, Li H, Cai R, Liu R, Meng F, Wang C, Zhu J-K, Lei M *, Xing W *. 2021 Mechanism of Phosphate Sensing and Signaling Revealed by Rice SPX1-PHR2 Complex Structure. Nat Commun.

2. Lin Y, Hu Q, Zhou J, Yin W, Yao D, Shao Y, Zhao Y, Guo B, Xia Y, Chen Q, Wang Y, Ye W, Xie Q, Tyler BM, Xing W*, Wang Y*. 2021. Phytophthora sojae effector Avr1d functions as an E2 competitor and inhibits ubiquitination activity of GmPUB13 to facilitate infection. Proc Natl Acad Sci U S A. 2021 Mar 9;118(10):e2018312118. 

3. Li J, Xin J, Zhao X, Zhao Y, Wang T, Xing W*, Tao X*. 2021. Expression, purification and crystallization of the N-terminal Solanaceae domain of the Sw-5b NLR immune receptor. Acta Crystallogr F Struct Biol Commun. 77(Pt 1):8-12.

4. Wang F, Fang J, Guan K, Luo S, Dogra V, Li B, Ma D, Zhao X, Lee KP, Sun P, Xin J, Liu T, Xing W*, Kim C*. 2020. The Arabidopsis CRUMPLED LEAF protein, a homolog of the cyanobacterial bilin lyase, retains the bilin-binding pocket for a yet unknown function. Plant J. 104(4):964-978.

5. Lin L, Zhang C, Chen Y, Wang Y, Wang D, Liu X, Wang M, Mao J, Zhang J, Xing W, Liu L, Li J. 2019. PAWH1 and PAWH2 are plant-specific components of an Arabidopsis endoplasmic reticulum-associated degradation complex. 2019. Nat Commun. 10(1):3492. 

6. Guo B, Wang H, Yang B, Jiang W, Jing M, Li H, Xia Y, Xu Y, Hu Q, Wang F, Yu F, Wang Y, Ye W, Dong S, Xing W*, Wang Y*. 2019. Phytophthora sojae Effector PsAvh240 Inhibits Host Aspartic Protease Secretion to Promote Infection. Mol Plant. 12(4):552-564. 

7.Chen W, Gong P, Guo J, Li H, Li R, Xing W, Yang Z, Guan Y. 2018. Glycolysis regulates pollen tube polarity via Rho GTPase signaling. PLoS Genet. 14(4)

8. Rosas-Diaz T, Zhang D, Fan P, Wang L, Ding X, Jiang Y, Jimenez-Gongora T, Medina-Puche L, Zhao X, Feng Z, Zhang G, Liu X, Bejarano ER, Tan L, Zhang H, Zhu JK, Xing W, Faulkner C, Nagawa S, Lozano-Duran R. 2018. A virus-targeted plant receptor-like kinase promotes cell-to-cell spread of RNAi. Proc Natl Acad Sci U S A. 115(6):1388-1393.

9. Huang J, Gu L, Zhang Y, Yan T, Kong G, Kong L, Guo B, Qiu M, Wang Y, Jing M, Xing W, Ye W, Wu Z, Zhang Z, Zheng X, Gijzen M, Wang Y, Dong S. 2017. An oomycete plant pathogen reprograms host pre-mRNA splicing to subvert immunity. Nat Commun. 8(1):2051.

10. Nangle S, Xing W*, Zheng N*. 2013. Crystal structure of mammalian cryptochrome in complex with a small molecule competitor of its ubiquitin ligase. Cell Res. 23(12):1417-1419.

11. Xing W, Busino L, Hinds TR, Marionni ST, Saifee NH, Bush MF, Pagano M, Zheng N. 2013. SCF(FBXL3) ubiquitin ligase targets cryptochromes at their cofactor pocket. Nature. 496(7443):64-68.

12. Xing W, Zou Y, Liu Q, Liu J, Luo X, Huang Q, Chen S, Zhu L, Bi R, Hao Q, Wu JW, Zhou JM, Chai J. 2007. The structural basis for activation of plant immunity by bacterial effector protein AvrPto. Nature. 449(7159):243-247.

13. Xiang T, Zong N, Zou Y, Wu Y, Zhang J, Xing W, Li Y, Tang X, Zhu L, Chai J, Zhou JM. 2008.Pseudomonas syringae effector AvrPto blocks innate immunity by targeting receptor kinases. Curr Biol. 18(1):74-80.

14. Liu HL, Zhou HN, Xing WM, Zhao JF, Li SX, Huang JF, Bi RC. 2004. 2.6 A resolution crystal structure of the bacterioferritin from Azotobacter vinelandii. FEBS Lett. 573(1-3):93-98.


更新时间:2022年1月