张辉

发布者:网站管理员发布时间:2019-03-15浏览次数:14667


1. 个人简介:

张辉博士,教授,植物学专业/博士生导师zhanghui29@shnu.edu.cn

教育经历:

2006-2012,博士,上海交通大学

2003-2006,硕士,宁夏大学

工作经历:

2019-至今,上海师范大学教授

2017-2019,中科院上海植物逆境生物学研究中心青年研究组长

2015-2017,普渡大学博士后

2012-2015,中科院上海植物逆境生物学研究中心博士后

2. 主要研究方向:

[1] 基因编辑技术开发。

[2]水稻基因编辑种质创新。

[3] 花卉基因编辑种质创新。

3. 代表性科研项目:

[1] 多基因编辑技术开发,上海市农业科技创新项目,2023-2026

[2] Wx等位变异的高效创制及其在水稻品质改良中的应用研究,国家自然科学基金面上项目,2022-2025

[3] 水稻miR156调控根系发育的分子机制,国家自然科学基金面上项目,2019-2022

4. 代表性论文著作:(*为通讯作者)

  • Sun, Y., Hong, Z., Wang, W., Zhang, H., Ren, X., He, X., Kan, T., Fan, Y., Wang, C., Cao, Y and Zhang H*. (2025). Establishment of an efficient and versatile genome editing platform for L. ruthenicum. Plant Physiology, kiaf486.

  • Xue, Y., Wang, C., Ge, R., Lu, S., Ni, J., Duan, Y., Hong, Z., and Zhang, H*. (2025). Efficient creation of decorative double‐flowered petunia through CRISPR/Cas9‐mediated simultaneous editing of PMADS3 and FBP6 genes. Plant Biotechnology Journal 23, 4350.

  • Wei, C., Wang, C., Jia, M., Guo, H.X., Luo, P.Y., Wang, M.G., Zhu, J.K., and Zhang, H*. (2021). Efficient generation of homozygous substitutions in rice in one generation utilizing an rABE8e base editor. Journal of integrative plant biology 63, 1595-1599.

  • Zhang, J., Zhou, Z., Bai, J., Tao, X., Wang, L., Zhang, H*., and Zhu, J.-K. (2020). Disruption of MIR396e and MIR396f improves rice yield under nitrogen-deficient conditions. National science review 7, 102-112.

  • Wu, J., Chen, C., Xian, G., Liu, D., Lin, L., Yin, S., Sun, Q., Fang, Y., Zhang, H*., and Wang, Y. (2020). Engineering herbicide‐resistant oilseed rape by CRISPR/Cas9‐mediated cytosine base‐editing. Plant Biotechnology Journal 18, 1857.

  • Zhang, H., Zhang, J., Yan, J., Gou, F., Mao, Y., Tang, G., Botella, J.R., and Zhu, J.-K. (2017). Short tandem target mimic rice lines uncover functions of miRNAs in regulating important agronomic traits. Proceedings of the national academy of sciences 114, 5277-5282.

  • Zhang, H., Gou, F., Zhang, J., Liu, W., Li, Q., Mao, Y., Botella, J.R., and Zhu, J.K. (2016). TALEN‐mediated targeted mutagenesis produces a large variety of heritable mutations in rice. Plant biotechnology journal 14, 186-194.

  • Zhang, H., Zhang, J., Wei, P., Zhang, B., Gou, F., Feng, Z., Mao, Y., Yang, L., Zhang, H., and Xu, N. (2014). The CRISPR/C as9 system produces specific and homozygous targeted gene editing in rice in one generation. Plant biotechnology journal 12, 797-807.

  • Zhang, H., Xu, C., He, Y., Zong, J., Yang, X., Si, H., Sun, Z., Hu, J., Liang, W., and Zhang, D. (2013). Mutation in CSA creates a new photoperiod-sensitive genic male sterile line applicable for hybrid rice seed production. Proceedings of the National Academy of Sciences 110, 76-81.

  • Zhang, H., Liang, W., Yang, X., Luo, X., Jiang, N., Ma, H., and Zhang, D. (2010). Carbon starved anther encodes a MYB domain protein that regulates sugar partitioning required for rice pollen development. The Plant Cell 22, 672-689.

5. 获奖情况:

明治生命科学奖

上海市“浦江学者”

上海高校特聘教授

上海师范大学“王乐三奖教金”

6. 代表性授权专利:

[1] 张辉, 汪冲, 罗鹏宇, 张亚军 一种CRISPR/Cas9介导的植物多基因编辑载体的构建方法和应用,专利号:ZL 202110773909.0

[2] 张大兵、张辉、梁婉琪、袁政,调控温光敏核不育的蛋白编码序列专利号:ZL200710172593.X

[3] 张大兵、梁婉琪、袁政、张辉,基于水稻的osms4突变体的制种、繁种及两系杂交育种方法,专利号:ZL201110431162.7

[4] 吴健、霍诗诗、王幼平、张辉、倪萍 基于基因编辑的BnALS1突变型基因、蛋白及其应用,专利号:CN111118060A


更新时间:2025年10月